Description
Noopept (GVS-111) is a synthetic dipeptide derivative of the cyclic prolyl-glycine pyroglutamate family, developed by the Russian Academy of Sciences as a structural analog of piracetam with significantly enhanced potency. The compound is rapidly hydrolyzed in vivo to cycloprolylglycine (cPG), an endogenous neuropeptide that is itself the proposed primary active metabolite. Noopept is studied in preclinical research as a nootropic and neuroprotective compound with reported effects on BDNF and NGF expression, NMDA receptor modulation, antioxidant activity, and cognitive performance in models of cerebral ischemia, traumatic brain injury, and Alzheimer’s-like neurodegeneration. Its small molecular weight (~318 Da) supports rapid absorption and blood-brain barrier penetration, with effects reported at significantly lower doses than racetam-class comparators in published research.
Benefits (Research Focus)
• Studied as a synthetic piracetam-class nootropic dipeptide with enhanced potency
• Investigated for BDNF and NGF expression upregulation in cortical and hippocampal models
• Explored for NMDA receptor modulation and AMPA receptor potentiation
• Examined for neuroprotection in cerebral ischemia and traumatic brain injury models
• Researched for antioxidant activity and lipid peroxidation reduction in brain tissue
What Researchers Look At
• Cycloprolylglycine (cPG) plasma and brain concentration following administration
• BDNF, NGF, and CREB pathway transcriptional response
• Cognitive performance endpoints in Morris water maze and passive avoidance tasks
• Cerebral blood flow and microcirculation in ischemia-reperfusion models
• Comparative pharmacology versus piracetam, aniracetam, and phenylpiracetam
Quick Specs
• Form: Gelatin capsule
• Strength: 20 mg / capsule
• Quantity: 30 capsules per bottle
• Excipient: Microcrystalline cellulose (MCC) — pharmaceutical-grade filler
• Purity: ≥99%
• Storage: Store in a cool, dry, dark place
Identity Basics
• Compound: Noopept
• Synonyms: GVS-111; N-phenylacetyl-L-prolylglycine ethyl ester; Omberacetam
• Class: Synthetic dipeptide nootropic; piracetam-class racetam analog
• Chemical Formula: C₁₇H₂₂N₂O₄
• Molecular Weight: 318.37 g/mol
• CAS: 157115-85-0
⚠️ Disclaimer
- This product is intended for laboratory research use only.
- Not for human or veterinary use.
- Not approved for diagnostic, therapeutic, or medical applications.
- Handle using appropriate laboratory safety procedures and personal protective equipment.
