Description
Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide first isolated from the brain in the 1970s.
Research interest centers on its role in sleep regulation, circadian rhythm balance, stress response, and recovery support.
Product Highlights
- Each vial contains 10 mL solution (~100 sprays)
- Each spray delivers 0.1 mL = 50 mcg DSIP
- Total DSIP Content: 5 mg per vial
- Specialized pharmaceutical-grade nasal solution — designed for comfort and ease on the nose
- Unlike many other nasal sprays, this formula avoids irritation and dryness
- Packaged in Class A, lead-free pharmaceutical glass bottles
- Tamper/Child-Proof Cap + Orifice Reducer for integrity, sterility, and ease of use
Description
DSIP has been studied for its potential to influence natural sleep cycles, stress responses, and recovery pathways.
Interest continues in its neuromodulatory and circadian-regulating properties in preclinical and clinical research contexts.
Benefits
- Sleep regulation — studied for promoting deeper, more restorative sleep phases
- Stress response — linked to modulation of stress-related neuroendocrine activity
- Circadian rhythm balance — explored for normalizing disrupted sleep–wake cycles
- Recovery support — interest in improved resilience and recovery in fatigue models
- Neuromodulation — early research suggests possible interactions with opioid and NMDA pathways
Localized Effects with Nasal Spray
- Rapid uptake through the nasal mucosa
- Direct modulation of sleep-related neuropeptide and stress-response pathways
- Formulated with a specialized isotonic nasal vehicle to minimize irritation and dryness
What Researchers Use It For
- Regulation of sleep architecture, delta-wave activity, and circadian rhythms
- Interaction with corticotropin and stress hormone pathways
- Modulation of opioid peptide activity and pain-related signaling
- Potential antioxidant and neuroprotective roles in preclinical models
Identity & Specs
- Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Formula / M.W.: C35H48N10O15, ~848.8 g/mol
- CAS: 62568-57-4
- Form: Sterile nasal spray solution
- Net per vial: 10 mL (~100 sprays)
- Total Content: 5 mg DSIP per vial
- Purity: ≥99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2–8 °C, protect from light
Selected Research
- PubChem entry — chemical identity & registry:
https://pubchem.ncbi.nlm.nih.gov/compound/DSIP
- Original discovery (1977) — isolation and initial findings:
https://pubmed.ncbi.nlm.nih.gov/195032/
- Sleep studies review — DSIP in sleep regulation:
https://pubmed.ncbi.nlm.nih.gov/17184943/
- Neuroendocrine effects — corticotropin and stress hormone pathways:
https://pubmed.ncbi.nlm.nih.gov/16529992/
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.





