KPV Nasal Spray 10mg- 10ml

• KPV (Lys-Pro-Val) is a naturally occurring tripeptide fragment derived from the alpha-melanocyte-stimulating hormone (α-MSH). It is studied for its potent anti-inflammatory, antimicrobial, and wound-healing properties, with a strong safety profile observed in preclinical models.
  

  Product Highlights

  • Each vial contains 10 mL solution (~100 sprays)
  • Each spray delivers 0.1 mL = 100 mcg KPV
  • Total KPV Content: 10 mg per vial
  • Specialized pharmaceutical-grade nasal solution — designed for comfort and ease on the nose
  • Unlike many other nasal sprays on the market, this formula avoids irritation and dryness
  • Packaged in Class A, lead-free pharmaceutical glass bottles
  • Tamper/Child-Proof Cap + Orifice Reducer for integrity, sterility, and ease of use

  Description

  KPV is a bioactive tripeptide known for its anti-inflammatory and immunomodulatory effects. It is studied for its ability to inhibit pro-inflammatory cytokines, protect epithelial barriers, and promote healing in models of inflammation, infection, and tissue injury.

  Benefits

  • Anti-inflammatory — studied for reducing inflammatory cytokine expression (e.g., TNF-α, IL-1β, IL-6)
  • Wound healing — explored for accelerating epithelial repair and collagen synthesis
  • Antimicrobial — shows activity against bacterial and fungal pathogens in preclinical studies
  • Barrier protection — supports gut, skin, and mucosal integrity under stress conditions
  • Safe and stable — exhibits strong safety profile and stability in various formulations

  Localized Effects with Nasal Spray

  • Rapid uptake through the nasal mucosa
  • Direct action on inflammatory and immune-modulating pathways
  • Formulated with a specialized isotonic nasal vehicle to minimize irritation and dryness

  What Researchers Use It For

  • Research in inflammatory bowel disease, dermatitis, and mucosal inflammation models
  • Studies on antimicrobial and epithelial barrier protection mechanisms
  • Exploration of melanocortin receptor modulation in immune signaling
  • Tissue healing and repair under oxidative or inflammatory stress conditions

  Identity & Specs

  • Sequence: Lys-Pro-Val
  • Formula / M.W.: C17H31N5O4, ~369.47 g/mol
  • CAS: 72682-81-4
  • Form: Sterile nasal spray solution
  • Net per vial: 10 mL (~100 sprays)
  • Total Content: 10 mg KPV per vial
  • Purity: ≥99% (HPLC)
  • Identity: MS-verified (per COA)
  • Storage: Refrigerate 2–8 °C, protect from light

  Selected Research

  • PubChem entry — chemical identity: https://pubchem.ncbi.nlm.nih.gov/compound/9940460
  • Anti-inflammatory mechanisms of KPV: https://pubmed.ncbi.nlm.nih.gov/21763249/
  • Barrier protection and epithelial repair: https://pubmed.ncbi.nlm.nih.gov/24316118/
  • Melanocortin receptor and immune signaling studies: https://pubmed.ncbi.nlm.nih.gov/21925274/
  • Antimicrobial peptide activity review: https://pubmed.ncbi.nlm.nih.gov/25596211/

⚠️ Disclaimer

• This product is intended for laboratory research use only.

• Not for human or veterinary use.

• Not approved for diagnostic, therapeutic, or medical applications.

• Handle using appropriate laboratory safety procedures and personal protective equipment.