Pinealon — 20 mg

Pinealon (EDR tripeptide) is a short peptide made of Glutamic acid, Aspartic acid, and Arginine. It is studied for its role in neuroprotection, gene regulation, oxidative stress balance, and memory support.

Benefits

• Memory support — studied for improving recall and learning efficiency.
• Neuroprotection — linked to reducing oxidative DNA damage in neuronal cells.
• Stress resilience — explored for supporting brain function under stress conditions.
• Cognitive aging — interest in maintaining plasticity and performance in older models.
• Gene regulation — associated with modulation of pathways tied to neuroplasticity.

What researchers look at

• Preservation of dendritic spines and reduction of apoptosis in neuronal models.
• Regulation of oxidative stress and ROS levels in preclinical settings.
• Epigenetic and gene-expression shifts tied to neuroplasticity pathways.
• Animal models: improved offspring cognition after prenatal stress exposure.

Quick Specs

• Form: Lyophilized peptide
• Net per vial: 20 mg
• Purity: ≥99% (HPLC)
• Identity: MS-verified (per COA)
• Storage: 2–8 °C, protect from light

Identity Basics

• Sequence: Glu–Asp–Arg (EDR)
• Formula / M.W.: C15H26N6O8, ~406–418 g/mol (varies by counter-ion)
• CAS: 175175-23-2

Selected Research

• Review — EDR peptide & gene regulation; dendritic-spine preservation (Molecules, 2020):
  
  https://pmc.ncbi.nlm.nih.gov/articles/PMC7795577/
  
• Review — Neuroprotective tripeptides; epigenetic mechanisms (2021):
  
  https://pmc.ncbi.nlm.nih.gov/articles/PMC8227791/
  
• Rejuvenation Research (2011) — reduced ROS & improved viability under stress:
  
  https://pubmed.ncbi.nlm.nih.gov/21978084/
  
• Prenatal stress model — offspring cognition improved (2012):
  
  https://pmc.ncbi.nlm.nih.gov/articles/PMC3342713/
  
• Induced-neuron study (2024) — reduced oxidative DNA damage in neurons from elderly donors:
  
  https://pmc.ncbi.nlm.nih.gov/articles/PMC11546785/
  

⚠️ Disclaimer

• This product is intended for laboratory research use only.

• Not for human or veterinary use.

• Not approved for diagnostic, therapeutic, or medical applications.

• Handle using appropriate laboratory safety procedures and personal protective equipment.