Description
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from adrenocorticotropic hormone (ACTH 4β10). It is studied for its effects on attention, memory, stress resilience, and post-stroke recovery, with research interest in neurotrophin pathways.
Benefits
- Attention and focus β studied for enhancing task performance and cognitive clarity.
- Memory support β linked to improved recall and learning efficiency in research models.
- Stress resilience β explored for modulating responses to acute and chronic stress.
- Stroke recovery β clinical programs report increased BDNF and motor recovery benefits.
- Neuroplasticity β associated with BDNF/TrkB and NGF signaling pathways.
What researchers look at
- Mechanistic link to neurotrophins (BDNF/NGF) and plasticity pathways.
- Transcriptomic responses in ischemic cortex models.
- Clinical trials in Russia exploring cognition, attention, and stroke recovery.
- Anti-aggregation properties studied in AΞ²βmetal interaction models.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 10 mg
- Purity: β₯99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2β8 Β°C, protect from light
Identity Basics
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
- Formula / M.W.: C37H51N9O10S, ~813.9 g/mol
- CAS: 80714-61-0
Selected Research
- PubChem entry β chemical identity:
https://pubchem.ncbi.nlm.nih.gov/compound/Semax
- Ischemic stroke rehab study (2018) β BDNF increase & motor recovery:
https://pubmed.ncbi.nlm.nih.gov/29798983/
- Genome-wide transcriptomic responses (2014):
https://pmc.ncbi.nlm.nih.gov/articles/PMC3987924/
- Neurotrophin signaling (2006):
https://pubmed.ncbi.nlm.nih.gov/16996037/
- NGF/BDNF dynamics (2009):
https://pubmed.ncbi.nlm.nih.gov/19662538/
- AΞ²βmetal interaction study (ACS Chem Neurosci, 2021):
https://pubs.acs.org/doi/10.1021/acschemneuro.1c00707
β οΈ Disclaimer
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This product isΒ intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved forΒ diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.






