Description
KPV is a tripeptide fragment (Lys-Pro-Val) derived from α-MSH, studied extensively for its anti-inflammatory, gut-protective, and immunomodulatory properties. Research models explore KPV for its ability to reduce inflammatory cytokines, support epithelial barrier integrity, and influence innate immune pathways without the hormonal activity associated with full α-MSH.
Benefits
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Studied for powerful anti-inflammatory activity
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Explored for gut-lining protection and epithelial repair
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Interest in supporting immune regulation and cytokine balance
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Investigated for skin, gut, and systemic inflammatory models
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Does not exhibit melanocortin hormonal effects like α-MSH
What Researchers Look At
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Modulation of inflammatory cytokines (IL-6, TNF-α, IL-1β)
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Effects on epithelial barrier and wound-healing models
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Activity on MC1R receptor pathways
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Comparative outcomes vs. full α-MSH and related peptides
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Immune and autoimmune signaling research
Quick Specs
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Form: Capsules
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Net per Capsule: 500 mcg
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Quantity: 30
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Purity: ≥99% (HPLC)
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Identity: MS-verified (per COA)
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Storage: Cool, dry place; avoid heat & moisture
Identity Basics
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Sequence: Lys-Pro-Val
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Formula / M.W.: C17H31N5O4 • ~369.46 g/mol
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CAS: 162045-99-4
Selected Research (Copy/Paste Links)
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Anti-inflammatory effects of α-MSH fragments:
https://pubmed.ncbi.nlm.nih.gov/10998324/ -
KPV in epithelial wound healing:
https://pubmed.ncbi.nlm.nih.gov/19433895/ -
Immune modulation and cytokine suppression:
https://pubmed.ncbi.nlm.nih.gov/12197815/
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.
