Description
N-Acetyl Epithalon Amidate is a next-generation synthetic analog of the classic pineal bioregulator Epithalon, modified with both acetylation and amidation for enhanced stability and bioavailability in research environments. It’s studied for its potential to regulate circadian rhythm genes, protect telomere length, and modulate cellular repair and longevity mechanisms. Researchers are exploring this optimized version for its unique neuro-endocrine, mitochondrial, and anti-aging signaling effects.
Benefits
• Supports telomerase activity and DNA protection in cellular models.
• Promotes balanced sleep-wake cycles through pineal–melatonin gene expression.
• Explored for antioxidant and mitochondrial protective effects.
• Investigated for improved cellular regeneration and vitality markers.
• Studied for neuroprotective and endocrine-supportive properties.
What Researchers Look At
• Pineal peptide signaling and telomerase modulation.
• SIRT1 and FOXO gene expression pathways.
• Effects on oxidative stress and mitochondrial potential.
• Comparative half-life and tissue uptake vs standard Epithalon.
Quick Specs
Form : Lyophilized powder
Net per vial : 20 mg
Purity : ≥ 99% (HPLC)
Identity : MS-verified (COA)
Storage : Keep refrigerated (2–8 °C)
Identity Basics
Sequence : Ala-Glu-Asp-Gly-(acetyl-amidate derivative)
Formula : C₃₈H₅₉N₁₁O₁₅
Molecular Weight : ≈ 945 Da
CAS : unregistered (synthetic analog of 307297-39-8 Epithalon)
Selected Research
• Khavinson et al., Bull Exp Biol Med, 2003 — “Peptide Epitalon and Telomerase Activation.”
• Anisimov et al., Neuroendocrinology Letters, 2005 — “Pineal Peptides and Longevity Control.”
• Fedoreyev et al., Biochemistry (Moscow), 2017 — “Molecular stability of acetylated Epithalon analogs.”
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.
