Description
PT-141 (Bremelanotide) is a synthetic peptide derived from the melanocortin pathway. It is studied for its effects on sexual function, libido enhancement, and central nervous system modulation of arousal, acting directly on melanocortin receptors in the brain.
Benefits
- Libido enhancement β studied for increasing sexual desire in both men and women.
- Central action β works directly on the brainβs melanocortin system, unlike PDE5 inhibitors.
- Versatility β explored for arousal issues independent of vascular function.
- Research in both sexes β investigated for female sexual dysfunction as well as erectile function in men.
- Fast-acting β studied for acute improvements in sexual readiness.
What researchers look at
- Mechanism: melanocortin receptor (MC3/MC4R) agonism in the hypothalamus.
- Clinical trials for female sexual interest/arousal disorder (FSIAD).
- Studies in erectile dysfunction models independent of nitric oxide pathways.
- Exploration of central vs. peripheral arousal mechanisms.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 10 mg
- Purity: β₯99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2β8 Β°C, protect from light
Identity Basics
- Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH
- Formula / M.W.: C50H68N14O10, ~1025 g/mol
- CAS: 189691-06-3
Selected Research
- PubChem entry β chemical identity:
https://pubchem.ncbi.nlm.nih.gov/compound/16132394
- Clinical trial in female sexual dysfunction (2008):
https://pubmed.ncbi.nlm.nih.gov/18620008/
- Mechanism of action review β melanocortin pathways:
https://pubmed.ncbi.nlm.nih.gov/16197338/
- Preclinical erectile function studies:
https://pubmed.ncbi.nlm.nih.gov/10825311/
β οΈ Disclaimer
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This product isΒ intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved forΒ diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.





