Description
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the natural immunomodulatory peptide tuftsin. It is studied for its role in anxiety regulation, memory, and stress resilience, with additional interest in immune modulation.
Benefits
- Anxiety regulation β studied as a potential anxiolytic in clinical and preclinical research.
- Memory and learning β linked to enhanced recall and cognitive performance in models.
- Stress resilience β explored for maintaining balance under chronic stress conditions.
- Immune system balance β reported shifts in cytokine profiles toward a healthier immune response.
- Synergy with GABA pathways β transcriptomic data suggest modulation of GABA-related genes.
What researchers look at
- Impact on hippocampal BDNF expression and neurotrophin levels.
- Modulation of GABA-related genes and signaling pathways.
- Clinical comparisons to benzodiazepines in anxiety spectrum disorders.
- Immune modulation effects, shifting Th1/Th2 cytokine balance.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 13 mg
- Purity: β₯99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2β8 Β°C, protect from light
Identity Basics
- Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
- Formula / M.W.: C33H57N11O9, ~751.9 g/mol
- CAS: 129954-34-3
Selected Research
- PubChem β chemical identity:
https://pubchem.ncbi.nlm.nih.gov/compound/Selank
- Intranasal Selank and hippocampal BDNF increase (2008):
https://pubmed.ncbi.nlm.nih.gov/18841804/
- GABA pathway modulation (Front Pharmacol, 2017):
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00089/full
- Diazepam synergy study (2017):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322660/
- Immune modulation in anxiety-asthenic patients (2008):
https://pubmed.ncbi.nlm.nih.gov/18577961/
- Clinical combo data in anxiety spectrum (2015):
https://pubmed.ncbi.nlm.nih.gov/26356395/
β οΈ Disclaimer
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This product isΒ intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved forΒ diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.





