Description
Melanotan II (MT-2) is a synthetic analog of the melanocortin peptide hormone alpha-MSH. It is studied for its ability to stimulate melanogenesis (skin tanning), influence libido, and activate melanocortin receptors in the brain and skin.
Benefits
- Skin pigmentation — studied for stimulating melanin production leading to tanning effects.
- Libido enhancement — explored for central melanocortin receptor activation linked to arousal.
- Photoprotection — research interest in UV protection through melanin increase.
- Energy and appetite — melanocortin pathways tied to appetite and metabolic regulation.
- Sexual health — investigated alongside PT-141 for overlapping melanocortin activity.
What researchers look at
- Mechanism: binds melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
- Tanning and pigmentation effects studied in humans and animals.
- Explored in erectile dysfunction and libido studies.
- Investigations into photoprotection and metabolic roles.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 10 mg
- Purity: ≥99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2–8 °C, protect from light
Identity Basics
- Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-Pro-Val-NH2
- Formula / M.W.: C50H69N15O9, ~1024 g/mol
- CAS: 121062-08-6
Selected Research
- PubChem entry — chemical identity:
https://pubchem.ncbi.nlm.nih.gov/compound/16132393
- Skin pigmentation and tanning studies:
https://pubmed.ncbi.nlm.nih.gov/9261989/
- Photoprotection and melanin production:
https://pubmed.ncbi.nlm.nih.gov/11705092/
- Melanocortin receptor activity review:
https://pubmed.ncbi.nlm.nih.gov/16197338/
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.
