Description
ARA-290 is an 11-amino-acid synthetic peptide derived from erythropoietin (EPO), designed to retain tissue-protective and anti-inflammatory properties without stimulating red blood cell production. It is studied for its roles in immune modulation, nerve protection, and chronic inflammatory conditions.
Benefits
- Neuroprotection — studied for reducing nerve pain and supporting peripheral neuropathy recovery.
- Anti-inflammatory — explored for calming inflammatory pathways without hematopoietic effects.
- Immune balance — interest in restoring immune homeostasis in chronic conditions.
- Tissue repair — linked to protection in ischemic, cardiac, and renal models.
- Metabolic health — studied for effects in diabetes-related complications.
What researchers look at
- Non-erythropoietic derivative of erythropoietin acting via EPOR/CD131 receptor complex.
- Preclinical and early human trials in neuropathic pain and small fiber neuropathy.
- Exploration in inflammatory, ischemic, and metabolic disease models.
- Potential for tissue-protective effects without stimulating erythropoiesis.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 20 mg
- Purity: ≥99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2–8 °C, protect from light
Identity Basics
- Sequence: QEQLERALNSS
- Formula / M.W.: C53H83N15O18, ~1178 g/mol
- CAS: 873436-91-0
Selected Research
- PubChem entry — chemical identity:
https://pubchem.ncbi.nlm.nih.gov/compound/ARA-290
- Neuropathy and pain reduction clinical trial:
https://pubmed.ncbi.nlm.nih.gov/23473169/
- Tissue protection and immune modulation review:
https://pubmed.ncbi.nlm.nih.gov/21912174/
- Inflammation and ischemia models:
https://pubmed.ncbi.nlm.nih.gov/22819469/
⚠️ Disclaimer
-
This product is intended for laboratory research use only.
-
Not for human or veterinary use.
-
Not approved for diagnostic, therapeutic, or medical applications.
-
Handle using appropriate laboratory safety procedures and personal protective equipment.
