AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a research compound widely studied for its ability to activate AMP‑activated protein kinase (AMPK), a central regulator of cellular energy balance. In research models, AICAR is examined for its role in mitochondrial biogenesis, glucose uptake, and metabolic adaptation to energetic stress. It is frequently investigated in studies of endurance physiology, metabolic regulation, and cellular energy signaling.

Benefits (Research Focus)

• Studied for AMPK activation and cellular energy regulation
• Explored for mitochondrial biogenesis and metabolic efficiency
• Investigated for effects on glucose uptake and lipid metabolism
• Research interest in endurance physiology and energy adaptation
• Examined in metabolic syndrome and cellular stress models

What Researchers Look At

• AMPK signaling pathway activation
• Mitochondrial biogenesis and oxidative metabolism
• Glucose transport and metabolic flexibility
• Cellular adaptation to energetic stress

Quick Specs

• Form: Lyophilized powder
• Net per vial: 50 mg
• Purity: ≥99% (HPLC)
• Identity: MS‑verified (per COA)
• Storage: 2–8 °C, protect from light

Identity Basics

• Compound: AICAR (5‑Aminoimidazole‑4‑carboxamide ribonucleotide)
• Chemical Formula: C9H14N4O8P
• Molecular Weight: 338.21 g/mol
• CAS: 2627‑69‑2

⚠️ Disclaimer

• This product is intended for laboratory research use only.

• Not for human or veterinary use.

• Not approved for diagnostic, therapeutic, or medical applications.

• Handle using appropriate laboratory safety procedures and personal protective equipment.