Acetic Acid Water — 10mL Sterile Peptide Reconstitution Diluent

Acetic Acid Water is a specialty sterile 10mL diluent formulated for reconstitution of pH-sensitive peptides that require an acidic diluent environment for optimal stability. Standard bacteriostatic water (0.9% benzyl alcohol, pH ~5.7) is the industry-standard sterile diluent for most lyophilized peptide reconstitution, but certain research peptides — including AOD-9604, Tesamorelin, Fragment 176-191, and other acid-preferring peptides — have documented stability issues in neutral-pH aqueous solution and benefit from reconstitution in acidic diluent. This 10mL sterile presentation contains 0.6% glacial acetic acid USP in Type 1 deionized water at approximately pH 3, matching the standard compounding pharmacy acidified diluent formulation used for peptides requiring acidic reconstitution. The formulation is prepared through triple sterile filtration and contains no additional preservative — the acidic pH provides limited bacteriostatic protection, but the product should be discarded 28 days after opening. Stored at room temperature. This diluent is offered as a companion product to standard Bacteriostatic Water for Injection for laboratory research applications requiring acidic reconstitution of pH-sensitive lyophilized peptides.

Benefits (Research Focus)

• pH-sensitive peptide reconstitution — specialty diluent for peptides that require acidic reconstitution environment for optimal stability

• AOD-9604 and Fragment research — investigated as the appropriate reconstitution diluent for AOD-9604 (Fragment 176-191) and related growth hormone fragment research peptides

• Tesamorelin research — explored for Tesamorelin GHRH analog research reconstitution

• Companion diluent to bacteriostatic water — examined as the acidic-pH companion diluent for research peptides where standard bacteriostatic water causes stability issues

• Triple-filtered sterile format — researched in enhanced-sterility triple filtration format for research applications requiring high-purity sterile diluent

What Researchers Look At

• pH stability at approximately 3 across reconstitution stability windows

• Peptide reconstitution stability comparative research versus bacteriostatic water (0.9% benzyl alcohol pH ~5.7)

• Sterility maintenance across post-opening 28-day discard window (no added preservative)

• Comparative research versus other acidic diluent formulations (0.1% acetic acid, other pH ranges)

• Peptide-specific stability research for acid-preferring versus neutral-pH-preferring research peptides

Quick Specs

• Form: Sterile liquid vial

• Volume: 10 mL per vial

• Container: Amber glass vial with rubber stopper

• Composition: Type 1 deionized water with 0.6% glacial acetic acid USP

• pH: Approximately 3 (acidic)

• Filtration: Triple filtered (sterile filtration)

• Preservative: None added (acidic pH provides limited bacteriostatic protection)

• Post-Opening Stability: Discard 28 days after opening

• Intended Use: Reconstitution of pH-sensitive peptides requiring acidic diluent

• Storage: Store at room temperature; protect from light

Compatible Research Peptides

• AOD-9604 — growth hormone fragment 176-191; established acid-preferring peptide requiring acidic reconstitution

• Tesamorelin — GHRH analog; benefits from acidic reconstitution for optimal stability

• Fragment 176-191 — growth hormone fragment; requires acidic diluent

• Certain GHRH analogs — where supplier COA specifies acidic reconstitution

• Other acid-preferring research peptides — always confirm reconstitution requirements against individual peptide supplier COA before use

Identity Basics

• Product Name: Acetic Acid Water (Sterile Acidified Peptide Reconstitution Diluent)

• Synonyms: Acidic peptide diluent; acetic acid reconstitution water; 0.6% acetic acid sterile water; acid reconstitution diluent

• Class: Sterile specialty pharmaceutical-grade diluent; acidified peptide reconstitution water

• Active Component: Glacial acetic acid USP at 0.6% concentration (approximately 60 mg/mL)

• Glacial Acetic Acid: CH₃COOH, MW ~60.05 g/mol, CAS 64-19-7 (USP monograph specification)

• Diluent Base: Type 1 deionized water (ASTM Type I deionized water for pharmaceutical use)

• Comparison to Bacteriostatic Water: Standard Bacteriostatic Water contains 0.9% benzyl alcohol at pH ~5.7 for 28-day multi-dose use. Acetic Acid Water contains 0.6% acetic acid at pH ~3 for acid-preferring peptides, no additional preservative, 28-day discard.

⚠️ Disclaimer

• This product is intended for laboratory research use only.
• Not for human or veterinary use.
• Not approved for diagnostic, therapeutic, or medical applications in this presentation.
• Contains acetic acid at acidic pH. Avoid contact with skin and eyes. Rinse thoroughly with water if contact occurs.
• Discard 28 days after opening. This product contains no additional preservative; the acidic pH provides limited bacteriostatic protection only.
• Handle using appropriate laboratory safety procedures and personal protective equipment.

Compatibility Notice: Not all lyophilized peptides benefit from acidic reconstitution. Confirm reconstitution requirements against individual peptide supplier COA before use. Standard Bacteriostatic Water (0.9% benzyl alcohol) remains the appropriate diluent for most research peptides.

Third-Party Testing

• [COA and sterility verification documentation for the Acetic Acid Water 10mL batch to be added once analytical testing is complete]