Description
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally derived from epithalamin, a natural pineal gland extract. It is studied for its potential effects on telomerase activation, cellular aging, and circadian rhythm regulation.
Benefits
- Cellular aging — studied for stimulating telomerase and supporting telomere length.
- Longevity research — explored for its role in lifespan and healthspan studies.
- Antioxidant activity — linked to reduced oxidative stress in preclinical models.
- Circadian rhythm support — studied for normalizing melatonin secretion and sleep cycles.
- Immune support — interest in modulating immune responses in aging research.
What researchers look at
- Activation of telomerase enzyme and extension of telomere length in cell studies.
- Increased lifespan and delayed onset of age-related changes in animal models.
- Normalization of circadian rhythms and melatonin secretion.
- Antioxidant and gene-expression modulation effects in lab settings.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 10 mg
- Purity: ≥99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2–8 °C, protect from light
Identity Basics
- Sequence: Ala-Glu-Asp-Gly (AEDG)
- Formula / M.W.: C14H22N4O9, ~390.35 g/mol
- CAS: 307297-39-8
Selected Research
- PubChem entry — chemical identity:
https://pubchem.ncbi.nlm.nih.gov/compound/Epitalon
- Telomerase activation and telomere length studies:
https://pubmed.ncbi.nlm.nih.gov/11795457/
- Lifespan extension in animal models (study):
https://pubmed.ncbi.nlm.nih.gov/10879644/
- Circadian rhythm and melatonin secretion:
https://pubmed.ncbi.nlm.nih.gov/12639494/
- Antioxidant and gene-expression effects:
https://pubmed.ncbi.nlm.nih.gov/15922078/
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.
