Description
SS-31 (Elamipretide) is a synthetic mitochondria-targeting tetrapeptide designed to bind cardiolipin within the inner mitochondria membrane. It is studied for its ability to enhance mitochondrial efficiency, reduce oxidative stress, and support cellular repair and energy metabolism.
Product Highlights
- Each vial contains 10 mL solution (~100 sprays)
- Each spray delivers 0.1 mL = 600 mcg SS-31
- Total SS-31 Content: 60 mg per vial
- Specialized pharmaceutical-grade nasal solution — designed for comfort and ease on the nose
- Unlike many other nasal sprays on the market, this formula avoids irritation and dryness
- Packaged in Class A, lead-free pharmaceutical glass bottles
- Tamper/Child-Proof Cap + Orifice Reducer for integrity, sterility, and ease of use
Description
SS-31 is a mitochondria-targeted peptide developed to stabilize cardiolipin, a vital phospholipid responsible for maintaining mitochondrial structure and function. It is studied for its role in improving ATP synthesis, reducing reactive oxygen species (ROS), and protecting against cellular and metabolic decline associated with aging and oxidative damage.
Benefits
- Mitochondrial protection — binds cardiolipin to support membrane integrity and energy transfer
- Reduces oxidative stress — limits ROS production and improves redox balance
- Enhances ATP generation — promotes efficient cellular respiration and energy production
- Tissue protection — studied for benefits in cardiac, neural, and muscular tissue resilience
- Supports anti-aging and metabolic health research — explored for longevity and mitochondrial optimization
Localized Effects with Nasal Spray
- Rapid uptake through the nasal mucosa
- Direct mitochondrial targeting across systemic and neural pathways
- Formulated with a specialized isotonic nasal vehicle to minimize irritation and dryness
What Researchers Use It For
- Studies on mitochondrial dysfunction, oxidative stress, and bioenergetic decline
- Models of heart failure, neurodegeneration, and age-related fatigue
- Research in skeletal muscle recovery and metabolic optimization
- Mechanistic studies on cardiolipin stabilization and ATP generation efficiency
Identity & Specs
- Sequence: D-Arg-2′6′-dimethylTyr-Lys-Phe-NH2
- Formula / M.W.: C34H49N9O5, ~623.8 g/mol
- CAS: 1270615-06-3
- Form: Sterile nasal spray solution
- Net per vial: 10 mL (~100 sprays)
- Total Content: 60 mg SS-31 per vial
- Purity: ≥99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: Refrigerate 2–8 °C, protect from light
Selected Research
- PubChem entry — chemical identity: https://pubchem.ncbi.nlm.nih.gov/compound/Elamipretide
- Mitochondrial protection via cardiolipin stabilization: https://pubmed.ncbi.nlm.nih.gov/25062012/
- Clinical cardiac function studies (ELBAT Trial): https://pubmed.ncbi.nlm.nih.gov/27510986/
- Mitochondrial efficiency and anti-aging review: https://pubmed.ncbi.nlm.nih.gov/32381287/
- Skeletal muscle function and endurance research: https://pubmed.ncbi.nlm.nih.gov/29321136/
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.
