Pancreagen — 20mg | KEDW Khavinson Pancreatic Peptide

Pancreagen (also known as Pancragen or Pankragen) is a synthetic tetrapeptide bioregulator developed by the Khavinson group at the St. Petersburg Institute of Bioregulation and Gerontology in Russia. Belonging to the same “Khavinson cytomedin” class as Epithalon, Cortagen, Pinealon, and Chonluten, Pancreagen is the tetrapeptide identified by Khavinson and colleagues as the pancreatic tissue-derived peptide bioregulator. The compound consists of the sequence Lys-Glu-Asp-Trp (KEDW) and is proposed to function through tissue-specific gene expression modulation in pancreatic cell populations. Pancreagen has been investigated in the Russian academic literature (Bulletin of Experimental Biology and Medicine; Khavinson and colleagues) for pancreatic cell biology research, exocrine and endocrine pancreatic tissue gene expression, and age-associated pancreatic cell function in preclinical research models. Like other Khavinson short-peptide bioregulators, Pancreagen is studied primarily as a research tool for tissue-specific peptide pharmacology rather than as a defined receptor agonist.

Benefits (Research Focus)

• Pancreatic cell biology research — studied for short-peptide bioregulator effects on pancreatic cell populations

• Gene expression modulation — investigated for tissue-specific gene expression in pancreatic cell research models

• Khavinson SAR research — explored alongside other Khavinson short-peptide bioregulators for structure-activity studies

• Tissue-specific peptide signaling — examined as a “cytomedin” / cytogen class compound for tissue-selective gene expression research

• Age-associated cellular research — researched for pancreatic cell biology endpoints in aged tissue research models

What Researchers Look At

• Pancreatic cell gene expression panels and tissue-selective signaling

• Comparative pharmacology versus other Khavinson short-peptide bioregulators

• Cellular proliferation and viability markers in pancreatic cell culture systems

• Aged-tissue model responses versus young-tissue models

• Tetrapeptide stability and pharmacokinetics in solution chemistry research

Quick Specs

• Form: Lyophilized white powder

• Net Peptide Content: 20 mg per vial

• Quantity: 1 vial

• Appearance: White to off-white lyophilizate

• Reconstitution: Bacteriostatic or sterile water (added by the end researcher)

• Purity: ≥99% by HPLC

• Identity: MS-verified (per COA)

• Storage: Protect from light

Identity Basics

• Compound: Pancreagen

• Synonyms: Pancragen; Pankragen; KEDW peptide; Lys-Glu-Asp-Trp tetrapeptide; Khavinson pancreatic peptide bioregulator

• Class: Synthetic tetrapeptide; Khavinson bioregulator / cytomedin class; pancreatic tissue-targeted

• Sequence: Lys-Glu-Asp-Trp (KEDW) — 4 amino acids

• Origin: Khavinson group, St. Petersburg Institute of Bioregulation and Gerontology (Russia)

• Formula / M.W.: C₂₅H₃₅N₇O₉, ~561.59 g/mol (verify against batch COA)

• CAS: Not formally assigned (peptide bioregulator class)

⚠️ Disclaimer

• This product is intended for laboratory research use only.
• Not for human or veterinary use.
• Not approved for diagnostic, therapeutic, or medical applications.
• Handle using appropriate laboratory safety procedures and personal protective equipment.

COA Verification Notice: Even if the vial label or product image states a certain concentration, always go by the COA for the true verified value. We reference the COA to determine the verified concentration and purity of each product, regardless of what the label or product image indicates.

Janoshik COA — Third-Party Testing