Description
5-Amino-1MQ is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). It is studied for its role in regulating fat metabolism, increasing cellular NAD+ availability, and supporting metabolic health. Research interest includes weight management, energy balance, and healthy aging.
Benefits
- Weight management — studied for reducing fat cell size and improving body composition.
- NAD+ metabolism — explored for boosting NAD+ salvage pathway efficiency.
- Energy support — linked to greater mitochondrial function and cellular energy.
- Metabolic health — interest in glucose regulation and insulin sensitivity.
- Healthy aging — studied in the context of metabolic slowdown and fat accumulation with age.
What researchers look at
- Mechanism: NNMT inhibition leading to improved NAD+ salvage pathway efficiency.
- Preclinical studies showing reduction of white adipose tissue mass.
- Role in obesity and metabolic syndrome research.
- Exploration of longevity and healthy aging applications.
Quick Specs
- Form: Lyophilized peptide
- Net per vial: 10 mg
- Purity: ≥99% (HPLC)
- Identity: MS-verified (per COA)
- Storage: 2–8 °C, protect from light
Identity Basics
- Type: Synthetic small molecule (non-peptide)
- Formula / M.W.: C6H8N4, ~136 g/mol
- CAS: 3731-56-8
Selected Research
- NNMT inhibition and fat metabolism:
https://pubmed.ncbi.nlm.nih.gov/30518665/
- NAD+ metabolism and energy balance:
https://pubmed.ncbi.nlm.nih.gov/27810927/
- Preclinical obesity and metabolic studies:
https://pubmed.ncbi.nlm.nih.gov/30361205/
⚠️ Disclaimer
-
This product is intended for laboratory research use only.
-
Not for human or veterinary use.
-
Not approved for diagnostic, therapeutic, or medical applications.
-
Handle using appropriate laboratory safety procedures and personal protective equipment.
Even if the vial label or product image states a certain concentration, always go by the COA for the true value. We reference the COA to determine the verified concentration and purity of each product, regardless of what the label or picture indicates.
