Description
Humanin is a mitochondrial-derived peptide (MDP) identified within the 16S rRNA region of mitochondrial DNA. It is studied for its cytoprotective, neuroprotective, and metabolic regulatory effects. Research highlights its ability to counter oxidative stress, support mitochondrial signaling, and promote cell survival under adverse conditions.
Benefits
• Studied for mitochondrial protection and oxidative stress resistance
• Explored for supporting healthy cellular metabolism and energy balance
• Research interest in neuroprotection and longevity pathways
• May influence IGF-1 and AMPK signaling in metabolic models
• Considered part of the “mitochondrial peptide” family linked to longevity science
What Researchers Look At
• Mitochondrial-derived peptides and their role in stress adaptation
• Interaction with apoptotic and insulin-signaling pathways
• Cytoprotective effects in neuronal and cardiac cell models
• Comparative studies with MOTS-c and SHLP family peptides
Quick Specs
• Form: Lyophilized peptide
• Net per vial: 10 mg
• Purity: ≥99% (HPLC)
• Identity: MS-verified (per COA)
• Storage: 2–8 °C, protect from light
Identity Basics
• Sequence: MAPRGFSCLLLLTSEIDLPVKRRA
• Formula / M.W.: C140H239N41O45S, ~2682.9 g/mol
• CAS: 831115-76-1
Selected Research
• Mitochondrial peptide signaling and protection: PubMed
• Humanin in neuroprotection and aging: PubMed
• Insulin sensitivity and metabolic regulation studies: PubMed
⚠️ Disclaimer
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This product is intended for laboratory research use only.
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Not for human or veterinary use.
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Not approved for diagnostic, therapeutic, or medical applications.
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Handle using appropriate laboratory safety procedures and personal protective equipment.
